Good security config, as already suggested, also I advise you to remove Iolo SM because of possible problems that it might cause.
Optimization softwares do not bring tangible improvements on modern operating systems and also, Iolo SM has background active processes that consume resources.
The idea that a software can improve stability and performance of Windows is hard to die.
Just add CCleaner and you're ok.
You can switch to uBlock Origin and evaluate the difference.