ThanksNano Adblocker. It's uBlock Origin + a few more tricks to better integrate with Nano Defender. Nano Adblocker also has more up to date lists (anti-mining), faster update cycle, configured for privacy out of the box. I would say if you use Nano Defender (and you really should), definitely use Nano Adblocker. If you don't, stick with uBlock Origin.
I have uBlock Origin + Nano Defender. I'll wait for a few more releases of Nano Adblocker before switching over