Hi,
Many people like Windows Defender however I really recommend using a different Antivirus for real-time protection (either you use this or nothing as it looks like you haven't installed any Antivirus software). I recommend taking a look into one of the following Internet Security products: ESET Smart Security, Kaspersky Internet Security or Emsisoft Internet Security.
I said "Internet Security" because this includes both Antivirus and Firewall protection. All 3 of those products are well known and have saved people from many infections. That's not to say that all the others are bad, but they are just particular products which I know that many people are satisfied with, I personally like and were at the top of my head (however I wouldn't have mentioned them if I thought they were bad).
Please only use one of those products. If you do not want to purchase security (there may be many reasons for this, and I would totally understand), you could look into using a free Antivirus combined with a free Firewall product. Such as using: Avast Free Antivirus, alongside Comodo Firewall (or another firewall you like or someone suggests).
As well as this, I recommend you use a few scanners on-demand (I did notice Spybot 2 on your configuration). On-demand means you scan with them, but they do not have any real-time protection/other protection settings enabled working in "real-time". Using multiple Antivirus products can cause issues (including but not limited to system slowdown), which is why on-demand scanning is so popular. I recommend looking into one - three of the following scanners I mention: Malwarebytes Free (you just scan with it, you do not need the Professional version), HitmanPro, Emsisoft Emergency Kit (If you decide to ue Emsisoft Internet Security, this is not necessary), Zemana Antimalware, ESET Online Scanner (if you decide to use ESET Smart Security, this is not necessary), HerdProtect.
I recommend getting another backup & recovery software as well as having system restore. System restore does not always work successfully. It's always good to have a secondary backup say on case of your personal documents, for example.
For system optimisation & cleaning, I recommend CCleaner. You can read more about it here:
https://www.piriform.com/ccleaner/download
For your extensions, you may want to look into HTTSEverywhere. You can read more about it here:
https://www.eff.org/Https-Everywhere
The only person who should decide on the software you use is you. Try some out, experiment with the different Antivirus/Internet Security products. Whichever one you like best, you can use.
Hope I helped,
Cheers.