What edition and version of Windows are you running ?
Why do you consider your Computer Knowledge to be Advanced ?
Why is your UAC disabled ? I strongly suggest you to enable it.
What was your last known malware infection ?
What version of Internet Explorer are you running ?
I strongly suggest you to uninstall a few more plugins to your browsers to enhance your browsing protection : HTTPSEverywhere, Ghostery, WOT (Web of Trust), etc.