Thanks folks. The reason I posted was not so much to get help but to make people aware that following the recipe on the Thread-How-to-completely-remove-ZeroAccess-Sirefef-rootkit-Removal-Guide wasn't necessarily going to result in a successful outcome.
As far as staying safe on line is concerned, I tend not to have problems myself as I'm fairly aware of the need to be risk-averse. The system with the problems belongs to a son-in-law. It's back working again but, because there was no installation disk, it's in the state it came out of the factory about six years ago as far as the software installation is concerned. And, yes, I did do a backup before I started so I could restore his data - not just 'My Documents' but C:\Documents & Settings\{username} & C:\Documents & Settings\Allusers so I could recover cookies, favourites, the desktop, Outlook Express data etc. etc. You have a bit selective in what you restore though or you can end up needing to go through the whole process again. (Norton Ghost 2003 can still be useful!)