Could consider taking Malwarebytes off and using Voodoshield ,better compliment to Windows defender,and lighter on your system,thou lol you have a powerhouse
Voodoshield is good approach with a simple PC i have a gaming PC with 7
tb pc games steam, origin, epic,gog etc. I think it will be hassle.
The same for the uac to maximum.
Also the the mbam has a very powerful tool the global ip web protection. If u ever bypassed, the ip protection will start to be chatty!
Also the malware-bytes is one of the third party tool that follows Microsoft guidelines and for me this is important.
also i don't like security that is passive and install drivers.
for example. northon power eraser install drivers if u make a rootkit scan.
zemana free install 2 drivers in ring1 (as i remember) that run always even if u close it or even if u uninstall it.
I always prefered
security to be build with a
stable machine in mind. Without the later security has no meaning.