does H C where ConfigureDefender blocks Windhawk MODS every WIndows update where it's Portmaster?
To see if H_C blocks the concrete application, you must inspect the H_C Log (Tools >> Blocked Events / Security Logs).
Depending on the settings, H_C can block the application "G:/Portable Apps/Start.exe".
Before inspecting the H_C Log, you can temporarily Switch OFF the H_C SRP restrictions to see if the issue disappears.