I realize that no one wants to use so-called "abandonware" eventhough behavior blockers, HIPS, and HIDS do not require signature updates to be fully effective. That said, there are still scenarios where a behavior blocker, set to max security levels, can be of use (Biozfear and McLovin proved that). I am thinking that if a PC is heavily infected and you would like to keep it in normal mode while disinfecting, TF, or other behavior blockers could be handy on a USB, so you can knock out some of the unwanted malicious background processes, thus creating a less hostile environment for your signature based AM and AV applications to operate and cleanse. Add "forced breach mode" in HitMan Pro to that strategy and it might all come in pretty handy.
http://www.scanwith.com/download/ThreatFire.htm
That is the link if you are interested in trying that. Save it to the desktop and then drag the TF package into your USB window. Simple as that.