Overkill and useless. CIS => The version with the antivirus?
If you are on Comodo Firewall, it is not CIS.
Then, WiseVector and Avast together, it's not a good idea, nor with Comodo (I tried both, I had big crashes).
I would recommend you to remove one of the 3 programs and to keep WiseVector as a complement if you keep Avast, or to couple it with another antivirus (like Microsoft Defender)