I used McAfee AntiVirus (not the suite), it's super light because it only scans files upon execution (that's fine by me) but my biggest grip with it, is that it has the worst user interface when it comes to whitelisting files:
1) The whitelist Window is super small and doesn't support DPI scaling for people with high resolution displays
2) You cannot exclude an entire folder, you have to exclude one file at at time
3) If the file you whitelisted gets updated, McAfee removes it from the whitelist, and you'd have to whitelist it again, which adds a lot of work as you have to whitelist the files with every update (ie. your VPN, or drivers folder, etc)