Yes, and default-deny e.g. AppGuard is the solution where user needs to lower its protection mode to Install and be certain that before installing/running .exe it is safe with other tools, or else you'll get infected and obviously it's user fault. For business users it's best where IT installs programms for you, configures it and lock downs employees PC. As a low technical skill cap home ape, I'd rather watch and follow development of new default-allow security modules made and more advanced Alien Ai.
The issue you raise here is not one of default-allow versus default-deny.
The software is unimportant. There is no substitute for user knowledge and experience - no matter what the security soft.
What is the user who doesn't know any better to do when their default-allow or default-deny solution does nothing while malware is running on the system but there are signs that most any user can see that something is wrong ? If they don't know then there isn't much that anyone can do for them.
And it is always the user's fault - whether it is default-allow or default-deny.
The solution is not to buy security softs x, y and z and then slap them onto a system.
The only solution is for people to be less dependent upon security softs (still use them, but at least have basic skills). That is the better solution for society, but since educating people who don't want to learn, who want a soft to tell them what to do is an impossible task, there isn't much that the industry can do - despite its best efforts.
Not to mention people are disappointed and keep complaining that their default-allow AV can be or was bypassed. Bypasses are never going to go away. No matter what the technology.
If users "want to use stuff," then they get what they get. Between Windows and users, those are the two predominant reasons why the malware problem is in the current state that we find it.