My take:
1. replace NVT with Hard_Configurator and add a default deny in user space and enable documents exploit
2. run ConfigureDefender and set level to HIGH, this includes enabling Windows Defender's Attack Surface Reduction protections for office)
3. Add all Office2007 to Windows Defender exploit protection and enable Code Integrity Guard (on top of ASR protect
4. Finally open trustcenter in all office applications disable Add-ins, Active-X and Macro's
5. When still feeling uncomfortable search for digital licenses (Office 2016 digital licenses are sold for less than 20 dollars).
Windows Defender free antivirus with ASR and Exploit protection for Office programs is one of the best anti-virus products when using Office.
RE:NVT - does not need signatures updates, but needs proper testing to check whether it is (still) compatible after Windows10 updates. The risk of locking yourself out of your PC due to update incompatibility is probably higher than running into an Office exploit with an anti-executable NVT locking down your system. So when you don't mind that risk, forget about the Office 2007 risk
Your Budweisier might taste the same but it is Belgian beer now, as an example that things may look the same but change under the hood (that is when you refer to the former US owned Bud beer and not the original Tsjech Budweiser)
