I would recommend that you add some on-demand scanners!
Examples: Malwarebytes, EEK, Malwarebytes JRT, AdwCleaner
Another great alternative you can add to your config is uBlock Origin, but Adguard is great as well.
Please use smartscreen - enable it as it is worth having on.
CCleaner and Wise Cleaner: both of these products are great, but both of them are not needed on your system. Personally, I would choose only one. If you choose CCleaner please update to the latest build as others have suggested.
Have you thought about adding HTTPS and NoScript to Chrome? Both of these are great for browser security.
Thanks for sharing your configuration!
Sincerely,
Lightning_Brian