I haven't done a clean install of Windows 10 on the main computer I use, for three years and don't plan on doing so for many years. I've got way too many programs installed for me to take the time to do a clean install and then reinstall any programs I use. It's about five different computers, that I've been running the same install of Windows on so far. When I get another computer, I replace its hard drive with my SSD.
When I first tried to install the April update a few weeks ago, it failed. I'll try again, now that's it's officially been released. If it fails again, I'll be looking at log files from the upgrade to (possibly) find the cause and fix it.