Good questions. So basically i use VS as an "antivirus" taking advantage of the VT engine and also VAi. I set VS in autopilot so i get the less alert possible so i usually don't see VS and get a decent level of extra protection. Keep in mind atm i use no antivirus.
I isolate everything that opens/downloads stuff from the internet. I added a few trusted vendors that i use applications from them so that i have automatic updates. I always use Lockdown mode without the gui. So basically nothing runs that i would not want to run.How do you like ReHIPS ?