Can you live with blocked the main program for productivity (your bread and butter)?
The main problem can be when using unsigned & non-prevalent applications. However, in most cases, there are as good but signed & prevalent alternatives. Of course, SAC can be useless for many users, too.
One can also submit files to Microsoft:
Submit a file for malware analysis - Microsoft Security Intelligence
Submit suspected malware or incorrectly detected files for analysis. Submitted files will be added to or removed from antimalware definitions based on the analysis results.
www.microsoft.com
