ConfigureDefender only will work if Windows Defender is your active AV. Are you using a 3rd party AV, or have you disabled Windows Defender somehow?I have hard_configurator version 4.2 on Windows 10 but 'Configure defender' and 'Run As Smartscreen' feature is not applicable on the tool .
is there any setting that I have to enable to turn on the feature?
Perhaps you have some other security software that is interfering? Try turning off other security, and see if it helps. If not, @Andy Ful to the rescue...'Run As Smartscreen' feature is not applicable on the tool