Short answer: Don't use it.Didn't notice if you enable the Windows update cleanup in the in-built cleaner it makes the cleaning process very slow compared to any other cleaner?
Source: Windows 10 and Storage SenseThe Disk Cleanup experience (“cleanmgr.exe”) is being deprecated. We’re retaining the Disk Cleanup tool for compatibility reasons. There’s no need to worry since Storage Sense’s functionality is a superset of what the legacy Disk Cleanup provides!
Source: Why does Disk Cleanup take so much time and cpu?Windows Updates Cleanup takes almost 100% CPU usage, it's all about WinSxS compression and reintegration of updates
Just be aware that Reg Organizer's registry cleaner has minor issues with false positives.In fact, I only trust two optimizers - Reg Organizer and Kerish Doctor.
Around 99% of registry cleaners have issues with false positives, meaning that they will at least sometimes want to delete valid registry keys. This is not a good thing, as sometimes they will delete important registry keys, which can cause problems.I had a bad experience once where the registry was corrupted which rendered some applications unusable..I guess that was in part my fault..